Prothrombin

A plasma protein that is the inactive precursor of thrombin. It is converted to thrombin by a prothrombin activator complex consisting of factor Xa, factor V, phospholipid, and calcium ions. Deficiency of prothrombin leads to hypoprothrombinemia.

Also Known As:

Factor II; Blood Coagulation Factor II; Differentiation Reversal Factor; Factor II, Coagulation; Factor, Differentiation Reversal; II, Coagulation Factor; Coagulation Factor II; Blood-coagulation factor II

Enzymes and Coenzymes: 1
- Enzyme Precursors: 724
  - Prothrombin: 5251
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Blood Proteins: 12459
    - Blood Coagulation Factors: 5376
      - Prothrombin: 5251
  - Protein Precursors: 37
    - Enzyme Precursors: 724
      - Prothrombin: 5251
Biological Factors: 2472
- Blood Coagulation Factors: 5376
  - Prothrombin: 5251

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Magali Carbonnier Research Topics

Disease

Drug/Important Bio-Agent (IBA)